In vitro postantibiotic effects of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis.

نویسندگان

  • Chiu-Yeung Chan
  • Carrie Au-Yeang
  • Wing-Wai Yew
  • Chi-Chiu Leung
  • Augustine F B Cheng
چکیده

Postantibiotic effects (PAEs) of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis ATCC 27294 were studied using a radiometric culture system. Rifapentine at 20 mg/liter gave the longest PAE (104 h) among the drugs used alone. The combinations of rifapentine plus isoniazid, rifapentine plus moxifloxacin, and isoniazid plus moxifloxacin gave PAEs of 136.5, 59.0, and 8.3 h, respectively.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 48 1  شماره 

صفحات  -

تاریخ انتشار 2004